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KMID : 0371320060700010053
Journal of the Korean Surgical Society
2006 Volume.70 No. 1 p.53 ~ p.58
Clinical Characteristics of Complicated Acute Cholecystitis and Its Outcome of Laparoscopic Cholecystectomy
À̾Ⱥ¹/Lee AB
ÀÌÇö±¹/¹Î¼®±â/À¯±Ç/Lee HK/Min SK/Yoo K
Abstract
Purpose: Complicated acute cholecystitis (AC) such as empyema or gangrene portends increased postoperative morbidity and mortality. The aim of this study is to investigate risk factors that contribute to the development of complicated AC and to evaluate the outcome of Laparoscopic cholecystectomy (LC) for complicated AC.

Methods: A total of 326 patients who underwent LC for AC between March 1997 and June 2002, were retrospectively reviewed. The risk factors associated with the development of complicated AC was investigated. The outcome of LC was compared between complicated AC (group A) and uncomplicated AC (group B).

Results: 87 patients (26.7%) developed complicated AC and the others 239 patients (73.3%) was in uncomplicated AC. On multivariate analysis, male gender (odds ratio; 1.76 P=0.029) and old age (odds ratio; 2.24 P=0.004) were predictive risk factors for complicated AC. The mean operation time in group A (111.2¡¾44.9 min) was longer compared to group B (95.3¡¾44.2 min)(P£¼0.01) and duration of hospital stay in group A (7.6¡¾4.6 days) were longer compared to group B (5.8¡¾3.0 days)(P£¼0.01). There were no significant differences in open conversion rates (3.4% vs 7.1%: P=0.22) and postoperative complications (12.2% vs 8.3%: P=0.32) between group A and group B.

Conclusion: Male gender and old age (¡Ã60) are risk factors associated with complicated AC. Outcome of LC in complicated AC was not significantly different from that of uncomplicated AC in terms of safety and feasibility. (J Korean Surg Soc 2006;70:53-58)
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